Best tip I can give you is read the manual and set it up the way that you like, there are preset mappers available to download on the Denon & VDJ (I think) websites, you can also download a DN-HC 4500 skin for VDJ which is really cool. Also if you are using it with Vista / 7 you need to adjust the jog trans to 12+, think the default setting is 4. It is possible that the previous owner has already done this however, the unit will crash intermittently if you don't. The manual explains how to do this. Best of luck with it, I find it to be a great unit.
Hey Mike, do you prefer the rmx or the hc4500?